ofatumumab SC, pazopanib. Both raises consequences of the other by immunosuppressive outcomes; danger of an infection. Use Warning/Observe. Take into account the risk of additive immune process consequences when coadministering immunosuppressive therapies with coadministration.
The authors declare the analysis was performed during the absence of any professional or monetary relationships that can be construed as a potential conflict of interest.
Steer clear of or Use Alternate Drug. If coadministration unavoidable, independent administration by no less than six hr ahead of or just after administration of P-gp substrates with slender therapeutic index.
QT interval need to be monitored when ezogabine is prescribed with brokers identified to raise QT interval.
Coadministration of palifermin inside 24 hr of chemotherapy resulted in amplified severity and period of oral mucositis.
pazopanib will boost the amount or influence of avanafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
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Concomitant use of fostamatinib might improve concentrations of P-gp/BCRP substrate medicines. Salvianolic Acid C Check for toxicities of P-gp/BCRP substrate SB 525334 drug that could need dosage reduction when offered concurrently with fostamatinib.
pazopanib will improve the level or result of isavuconazonium sulfate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
Watch Carefully (1)siponimod and pazopanib the two boost immunosuppressive results; threat of infection. Use Warning/Watch. Caution if coadministered as a consequence of additive immunosuppressive outcomes for the duration of these therapy and while in the weeks adhering to administration.
nizatidine will lessen the level or result of pazopanib by raising gastric pH. Applies only to oral method of both of those brokers.
eslicarbazepine acetate will minimize the extent or result of pazopanib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
Watch for toxicities of P-gp/BCRP substrate drug that could have to have dosage reduction when presented concurrently with fostamatinib.
macimorelin and pazopanib the two raise QTc interval. Dioscin Steer clear of or Use Alternate Drug. Macimorelin will cause a rise of ~eleven msec during the corrected QT interval. Steer clear of coadministration with medicine that lengthen QT interval, which could increase danger for producing torsade de pointes-style ventricular tachycardia.